Shree SKR Globals

Leugard 11.25mg Injection is given as an injection under the skin by a qualified medical professional.  Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Decreased libido, increased sweating, fatigue, muscle weakness, and hot flashes are some very common side effects of this medicine. The long-term use of medicine may cause weakened bones and a reduction in bone mineral density. You are advised to take vitamin D and calcium supplements while taking this medicine. It might cause menstrual periods to stop for a period of 7- 12 weeks, inform your doctor if menstrual bleeding continues even during the treatment.

Before taking this medicine, inform your doctor if you have a history of drinking alcohol, smoking, and osteoporosis. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Endace (Megestrol Acetate) 40mg Tablet is a progestin hormone used primarily to treat hormone-dependent cancers and to manage appetite loss and weight loss in certain medical conditions.

• Breast Cancer (advanced, hormone-dependent)

• Endometrial Cancer (advanced or recurrent)

• Appetite stimulation in patients with cachexia (severe weight loss) due to cancer, HIV/AIDS, or other chronic illnesses

Megestrol Acetate is a synthetic progestin that works by:

• Blocking estrogen activity, slowing cancer growth in hormone-sensitive tumors.

• Stimulating appetite and promoting weight gain in patients with severe weight loss.

• Breast Cancer: 40mg to 320mg per day, as prescribed.

• Endometrial Cancer: Usually 40mg–320mg daily in divided doses.

• Appetite Stimulation: Dosage varies based on condition.

• Can be taken with or without food.

• Weight gain, increased appetite

• Swelling (fluid retention), high blood pressure

• Nausea, upset stomach

• Hot flashes, dizziness

• Blood clot risk (deep vein thrombosis, pulmonary embolism)

• Not recommended for pregnant or breastfeeding women.

• Monitor for blood clot risks (especially in patients with heart disease).

• Use with caution in diabetes, as it may affect blood sugar levels.

Endace should be taken under strict medical supervision with regular follow-ups.

Canshield 50mg Injection contains Caspofungin Acetate, an echinocandin antifungal. It is often used when other antifungal treatments fail or are not suitable.

• Effective against Candida and Aspergillus infections.
• Administered intravenously under medical supervision.
• Typically used in hospitalized patients with serious fungal infections.

• Used to treat serious fungal infections such as invasive candidiasis, aspergillosis, and esophageal candidiasis.
• Works by inhibiting the fungal cell wall synthesis, making it effective against resistant fungal infections.

Product Description: Alfoo 10mg contains Alfuzosin 10mg, an alpha-blocker used to treat symptoms of benign prostatic hyperplasia (BPH), a condition in which the prostate gland is enlarged in men, causing difficulty in urination. Alfuzosin works by relaxing the muscles in the prostate and the bladder neck, making it easier to urinate and improving urine flow.

This medication is typically prescribed for men who have BPH, which can cause symptoms like frequent urination, a weak stream, or an inability to empty the bladder completely. Alfuzosin helps relieve these symptoms but does not shrink the prostate or prevent its further enlargement.

Common side effects of Alfoo 10mg include dizziness, headache, fatigue, or fainting, especially when standing up quickly (orthostatic hypotension). It is advised to rise slowly from a sitting or lying position to minimize the risk of dizziness.

Patients are recommended to take this medication as prescribed, usually once daily after a meal. Alfoo 10mg should not be taken on an empty stomach. It is also important to follow up with the doctor regularly to monitor the effectiveness of the treatment and adjust the dosage if necessary.

This medication may interact with other drugs, so it is important to inform the doctor of all other medications being taken. Additionally, Alfoo should be used with caution in individuals with a history of heart problems, and it is not suitable for use in women or children.

• How should I use this medicine:
• Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Do not cut, crush or chew this medicine. Take this medicine on an empty stomach, at least 1 hour before or 2 hours after meals. Do not take with food. Take your medicine at regular intervals. Do not take it more often than directed. Do not stop taking except on your doctor's advice. Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed. Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

Product Name: Tepastim 15mg Injection

Brand Name: Tepastim, Tepadina, Thioplex

Composition: Thiotepa (15mg)

Manufacturer/Marketer: Zydus Cadila

Packaging: To be provided (specify packaging details if available)

Treatment: Cancer (including breast cancer, ovarian cancer, and bladder cancer), bone marrow transplantation conditioning

Product Description: Tepastim 15mg Injection contains Thiotepa, an alkylating agent used in chemotherapy to treat various cancers such as breast, ovarian, and bladder cancer. It works by interfering with the growth of cancer cells, slowing or stopping their spread. Thiotepa is also used in high doses as part of conditioning treatment before bone marrow transplantation

• Note:
• Evertor is a prescription Drug and should be used under Proper Medical Guidance and Advice. Do not share the medicine with others, since they may be suffering from a problem that is not effectively treated by this drug.

Sigrima 420mg Injection

Brand Names: Sigrima, Perjeta (widely known brand based on composition)

Composition: Pertuzumab 420 mg

Strength: 420 mg/14 mL

Manufacturer: Glenmark Pharmaceuticals

Packaging: Typically available in a single-dose vial containing 14 mL of solution

Treatment: HER2-positive breast cancer

Product Description:
Sigrima 420mg Injection contains Pertuzumab, a monoclonal antibody that targets the human epidermal growth factor receptor 2 (HER2). Pertuzumab works by binding to the HER2 receptor, preventing it from pairing with other HER family receptors, which can lead to the growth of cancer cells. This action enhances the efficacy of other HER2-targeted therapies, such as trastuzumab, in treating HER2-positive breast cancer.

Common indications for Sigrima 420mg Injection include:

• HER2-Positive Breast Cancer: Used in combination with trastuzumab and docetaxel for the treatment of patients with HER2-positive metastatic breast cancer who have not received prior anti-HER2 therapy or chemotherapy for metastatic disease.
• Neoadjuvant Treatment: Used in combination with trastuzumab and chemotherapy as neoadjuvant treatment for patients with HER2-positive, locally advanced, inflammatory, or early-stage breast cancer at high risk of recurrence.

Dosage and Administration:

• For Adults: The initial loading dose is typically 840 mg administered as an intravenous infusion over 60 minutes, followed by a maintenance dose of 420 mg every 3 weeks.
• Administration: Sigrima is administered as an intravenous infusion by a healthcare professional in a clinical setting. The dosage and frequency depend on the specific condition being treated and the patient’s response to therapy.

Common side effects of Sigrima 420mg Injection may include:

• Diarrhea
• Fatigue
• Nausea
• Alopecia
• Rash
• Neutropenia
• Peripheral neuropathy

Cardiac function should be monitored closely during treatment, as HER2-targeted therapies can affect heart function.

Packaging:
Sigrima 420mg Injection is typically packaged in a single-use vial containing 14 mL of solution, designed for single-dose use.

Sigrima 420mg Injection is a crucial component in the treatment of HER2-positive breast cancer, particularly when used in combination with other targeted therapies like trastuzumab. Its role in both metastatic and early-stage breast cancer provides significant benefits, helping to improve survival rates and reduce the risk of cancer recurrence. Close monitoring of the patient’s cardiac function and adherence to the prescribed infusion schedule are essential for optimizing treatment outcomes while managing potential side effects